Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2010 Jul;94(2):485-8.
doi: 10.1016/j.fertnstert.2009.03.082. Epub 2009 May 13.

Time to pregnancy after a previous miscarriage in subfertile couples

Tessa Cox  1 , Jan-Willem van der Steeg, Pieternel Steures, Peter G A Hompes, Fulco van der Veen, Marinus J C Eijkemans, Jules H Schagen van Leeuwen, Cees Renckens, Patrick M M Bossuyt, Ben W J Mol
Affiliations
Free article
Multicenter Study

Time to pregnancy after a previous miscarriage in subfertile couples

Tessa Cox et al. Fertil Steril. 2010 Jul.
Free article

Abstract

Objective: To assess the time to spontaneous ongoing pregnancy after a previous miscarriage in subfertile couples.

Design: A prospective cohort study.

Setting: The study was conducted in 38 fertility centers in the Netherlands.

Patient(s): Subfertile couples who miscarried after completing their basic fertility work-up.

Intervention(s): Expectant management after a miscarriage.

Main outcome measure(s): Spontaneous ongoing pregnancy.

Result(s): We included 5,663 subfertile couples, of which 1,098 (19%) conceived spontaneously. Among these 1,098 couples, 199 (18%) miscarried and these couples were included in the present study. Follow-up was completed for 171 couples, of which 95 conceived again within 24 months of follow-up. Of these 95 pregnancies, 86 (91%) were ongoing. The cumulative spontaneous ongoing pregnancy rate (PR) after 24 months was 70% (95% confidence interval [CI] 59%-81%).

Conclusion(s): Subfertile couples, who experience a treatment-independent pregnancy resulting in a miscarriage, have very good prospects of a spontaneous ongoing pregnancy in the near future. This information is useful in counseling couples who had a miscarriage after a previous period of subfertility.

PubMed Disclaimer

Publication types