Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jun;191(2):63-6.
doi: 10.1016/j.cancergencyto.2009.01.013.

Telomere capture in hepatitis C infection

Lilach Goldberg-Bittman  1 , Aliza Amiel, Ruth Hadary, Moshe D Fejgin, Miriam Quitt, Yona Kitay-Cohen
Affiliations

Telomere capture in hepatitis C infection

Lilach Goldberg-Bittman et al. Cancer Genet Cytogenet. 2009 Jun.

Abstract

Broken chromosomes can acquire new telomeres by "telomere capture" (TC), and it has become possible to investigate the terminus in cytogenetically visible telomere rearrangements. The TC phenomenon was observed in malignant conditions. We evaluated the TC rate in hepatitis C virus (HCV) patients compared to non-Hodgkin's lymphoma patients, as well as relative to a control group. For this purpose, we used two Cytocell probes, 15qter and 13qter. Higher TC rates were found in the three study groups relative to the control group. Our results showed that HCV patients have some of the components that can initiate the cascade of events leading to malignancies.

PubMed Disclaimer

Publication types

LinkOut - more resources