Review
doi: 10.1093/rheumatology/kep101.
Epub 2009 May 15.
Methotrexate, rheumatoid arthritis and infection risk: what is the evidence?
Affiliations
- PMID: 19447771
- DOI: 10.1093/rheumatology/kep101
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Review
Methotrexate, rheumatoid arthritis and infection risk: what is the evidence?
Rheumatology (Oxford).
2009 Aug.
Abstract
Low-dose MTX administered weekly remains a mainstay in the therapy of RA. There is a belief amongst rheumatologists that RA patients taking MTX have both an increased risk and severity of infection. Here we review the published data on the risks of infection associated with the use of MTX in patients with RA and make some recommendations for managing MTX in patients with infection.
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