Meta-analysis on the effect of dopexamine on in-hospital mortality
- PMID: 19453310
- DOI: 10.1111/j.1365-2044.2009.05896.x
Meta-analysis on the effect of dopexamine on in-hospital mortality
Abstract
The objective of the study was to determine whether dopexamine alters in-hospital mortality. The following databases were searched, Embase (1974-July 2007), Medline (1950-July 2007), CINAHL, PubMed and Cochrane Clinical Register of Controlled Trials (CENTRAL). Two reviewers independently checked the quality of the studies and extracted data. Six randomised controlled trials totalling 935 patients were included. Mortality was not significantly different with dopexamine treatment (relative risk 0.75, 95% confidence interval 0.48-1.18, p = 0.22). In conclusion, dopexamine does not improve in-hospital mortality in patients undergoing major abdominal surgery and in the critically ill.
Comment in
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Meta-analyses of the effects of dopexamine in major surgery: do all roads lead to Rome?Anaesthesia. 2009 Jun;64(6):585-8. doi: 10.1111/j.1365-2044.2009.05965.x. Anaesthesia. 2009. PMID: 19453309 No abstract available.
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Dopexamine and survival: areas of consistency.Anaesthesia. 2009 Nov;64(11):1258; author reply 1259. doi: 10.1111/j.1365-2044.2009.06111.x. Anaesthesia. 2009. PMID: 19825065 No abstract available.
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