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Review
. 2008 Nov;2(6):211-9.
doi: 10.1111/j.1750-2659.2008.00053.x.

FluBlok, a recombinant hemagglutinin influenza vaccine

Manon M J Cox  1 , Peter A Patriarca, John Treanor
Affiliations
Review

FluBlok, a recombinant hemagglutinin influenza vaccine

Manon M J Cox et al. Influenza Other Respir Viruses. 2008 Nov.

Abstract

FluBlok, a recombinant trivalent hemagglutinin (HA) vaccine produced in insect cell culture using the baculovirus expression system, provides an attractive alternative to the current egg-based trivalent inactivated influenza vaccine (TIV) manufacturing process. FluBlok contains three times more HA than TIV and does not contain egg-protein or preservatives. This review discusses the four main clinical studies that were used to support licensure of FluBlok under the 'Accelerated Approval' mechanism in the United States.

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