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. 2009 Jul;6(7):2017-23.
doi: 10.1111/j.1743-6109.2009.01268.x. Epub 2009 Apr 24.

Vascular risk factors as predictors of sexual function following coronary artery bypass graft

Osama A Mohamed  1 , Hamed A Hamed, Mohamed Farid Roaiah, Tarek Helmy, Ali Mahran, Carol J Bennett
Affiliations

Vascular risk factors as predictors of sexual function following coronary artery bypass graft

Osama A Mohamed et al. J Sex Med. 2009 Jul.

Abstract

Introduction: A strong association between cardiovascular risk factors and erectile dysfunction (ED) was suggested. Coronary artery bypass grafting (CABG) is the gold standard for surgical myocardial revascularization.

Aim: We herein evaluate the impact of vascular risk factors on postoperative sexual functions in patients undergo CABG.

Main outcome measures: ED severity by the International Index of Erectile Function (IIEF-5) and penile duplex study.

Methods: The present study included 100 patients who underwent CABG. The patients were evaluated by an abridged form of the IIEF-5 questionnaire, followed by CABG. Six months after surgery the erectile function of all patients was re-evaluated utilizing the IIEF-5.

Results: Number of risk factors was significantly associated with postoperative change in IIEF-5 score (P = 0.02). A post hoc analysis of the association revealed that patients with one risk factor were significantly more likely to have increased IIEF-5 scores (N = 18), whereas those with two or more risk factors were significantly more likely to have decreased IIEF-5 scores (N = 21, P < 0.05). Furthermore, those with no risk factors were significantly more likely to be stable (N = 8) compared with those with more than two risk factors, who were more likely to have decreased scores (P < 0.05). The hierarchical logistic regression results showed that when examining all risk factors simultaneously, because of multicollinearity, only hyperlipidemia was significantly associated with postoperative ED (odds ratio [OR] = 11.33, confidence interval [CI] = 1.25, 102.82). Frequency of intercourse was also significantly associated with postoperative ED after controlling for risk factors (OR = 0.71, CI = 0.52, 0.97).

Conclusions: This data clearly shows that the number of cardiovascular risk factors is an essential predictive factor for sexual function following surgery. Only hyperlipidemia may play a predictive role for the future sexual function of patients undergo CABG.

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