Chronic suppurative otitis media
Abstract
Introduction: Chronic suppurative otitis media (CSOM) is a common cause of hearing impairment, disability, and poor scholastic performance, and can occasionally lead to fatal intracranial infections and acute mastoiditis, especially in resource-poor countries.
Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments for chronic suppurative otitis media in adults; and in children? We searched: Medline, Embase, The Cochrane Library and other important databases up to January 2007 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
Results: We found 48 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
Conclusions: In this systematic review we present information relating to the effectiveness and safety of the following interventions: ear cleansing, systemic antibiotics, topical antibiotics, topical antiseptics, topical corticosteroids, tympanoplasty (with or without mastoidectomy).
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References
-
- WHO. Chronic suppurative otitis media. Burden of illness and management options. 2004. http://www.who.int/child-adolescent-health/New_Publications/CHILD_HEALTH... (last accessed 8 November 2005).
-
- Homoe P. Otitis media in Greenland. Studies on historical, epidemiological, microbiological, and immunological aspects. Int J Circumpolar Health 2001;60(suppl 2):1–54. - PubMed
-
- Tos M. Sequelae of secretory otitis media and the relationship to chronic suppurative otitis media. Ann Otol Rhinol Laryngol 1990;99:18–19. - PubMed
-
- Daly KA, Hunter LL, Levine SC, et al. Relationships between otitis media sequelae and age. Laryngoscope 1998;108:1306–1310. - PubMed
-
- New Zealand Health Technology Assessment Clearing House. Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children. A critical appraisal of the literature (NZHTA report 3). Christchurch, New Zealand, June 1998. Available online at: http://nzhta.chmeds.ac.nz/publications/nzhta3.pdf (last accessed 8 November 2006). Search date 1998; primary sources English language articles in Medline, Cinahl, Healthstar, Current Contents (combined files), Cochrane Library Database of Abstracts of Reviews of Effectiveness, NHS Economic Evaluation Database, New Zealand Bibliographic Network, New Zealand Ministry of Health publications, United States National Institute of Health publications, Catalogues of New Zealand medical libraries, and publications and current projects by the International Network of Agencies for Health Technology Assessment (INAHTA).
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