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. 2009 Dec;15(12):1182-5.
doi: 10.1111/j.1469-0691.2009.02789.x. Epub 2009 May 16.

Molecular and phenotypic characterization of invasive group B streptococcus strains from infants in Norway 2006-2007

H Bergseng  1 , J E Afset, A Radtke, K Loeseth, R V Lyng, M Rygg, K Bergh
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Free article

Molecular and phenotypic characterization of invasive group B streptococcus strains from infants in Norway 2006-2007

H Bergseng et al. Clin Microbiol Infect. 2009 Dec.
Free article

Abstract

Multilocus sequence typing of an almost complete collection of invasive group B streptococcus (GBS) strains from infants in Norway, conducted in 2006-2007, revealed 27 sequence types (ST), of which 23 clustered into five clonal complexes. The case fatality rate of invasive GBS disease in infants was 16/98 (16.3%). Type V strains were predominant among strains resistant to erythromycin and clindamycin (11/18; 61.1%). All type V strains from fatal cases (5/16) were ST1, resistant to erythromycin and clindamycin, and belonged to three pulsed-field gel electrophoresis-clusters. Further analysis of virulence characteristics of these apparently highly virulent subtypes of type V, ST1 GBS strains is warranted.

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