doi: 10.1016/j.tig.2009.04.004.
Epub 2009 May 18.
Scaling laws in functional genome content across prokaryotic clades and lifestyles
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- PMID: 19457568
- DOI: 10.1016/j.tig.2009.04.004
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Scaling laws in functional genome content across prokaryotic clades and lifestyles
Trends Genet.
2009 Jun.
Abstract
For high-level functional categories that are represented in almost all prokaryotic genomes, the numbers of genes in these categories scale as power-laws in the total number of genes. We present a comprehensive analysis of the variation in these scaling laws across prokaryotic clades and lifestyles. For the large majority of functional categories, including transcription regulators, the inferred scaling laws are statistically indistinguishable across clades and lifestyles, supporting the simple hypothesis that these scaling laws are universally shared by all prokaryotes.
Comment in
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Regulome size in Prokaryotes: universality and lineage-specific variations.Trends Genet. 2009 Jul;25(7):285-6. doi: 10.1016/j.tig.2009.05.001. Epub 2009 Jun 18. Trends Genet. 2009. PMID: 19540614 No abstract available.
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