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. 2009 May 21:7:12.
doi: 10.1186/1478-4505-7-12.

Developing a conceptual framework for an evaluation system for the NIAID HIV/AIDS clinical trials networks

Jonathan M Kagan  1 , Mary Kane, Kathleen M Quinlan, Scott Rosas, William M K Trochim
Affiliations

Developing a conceptual framework for an evaluation system for the NIAID HIV/AIDS clinical trials networks

Jonathan M Kagan et al. Health Res Policy Syst. .

Abstract

Globally, health research organizations are called upon to re-examine their policies and practices to more efficiently and effectively address current scientific and social needs, as well as increasing public demands for accountability.Through a case study approach, the authors examine an effort undertaken by the National Institute of Allergy & Infectious Diseases (part of the National Institutes of Health, Department of Health & Human Services, United States Government) to develop an evaluation system for its recently restructured HIV/AIDS clinical trials program. The challenges in designing, operationalizing, and managing global clinical trials programs are considered in the context of large scale scientific research initiatives.Through a process of extensive stakeholder input, a framework of success factors was developed that enables both a prospective view of the elements that must be addressed in an evaluation of this research and a current state assessment of the extent to which the goals of the restructuring are understood by stakeholders across the DAIDS clinical research networks.

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Figures

Figure 1
Figure 1
Evolution of the NIAID HIV/AIDS clinical trials networks.
Figure 2
Figure 2
Process for developing an evaluation system.
Figure 3
Figure 3
Concept map of success factors.
Figure 4
Figure 4
DAIDS clinical trials networks logic model.
See this image and copyright information in PMC

References

    1. Hanney SR, Gonzalez-Block MA. Building health research systems to achieve better health. Health Res Policy Syst. 2006;4:10. doi: 10.1186/1478-4505-4-10. - DOI - PMC - PubMed
    1. Edgerton DEH. Before big science: the pursuit of modern chemistry and physics, 1800–1940. Ann Sci. 1999;56:107–107.
    1. Nash SJ, Stillman BW. Large-scale biomedical science: Exploring strategies for future research. Washington, DC, USA: The National Academies Press; 2003.
    1. Institute of Medicine . NIH extramural center programs. Washington, DC, USA: The National Academies Press; 2004. - PubMed
    1. Inventory and Evaluation of Clinical Research Networks Core and descriptive survey final report. 2006. http://www.clinicalresearchnetworks.org/documents/CDESum.pdf

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