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Review
. 2009 Jun;113(6):1341-1348.
doi: 10.1097/AOG.0b013e3181a71551.

In defense of magnesium sulfate

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Review

In defense of magnesium sulfate

John P Elliott et al. Obstet Gynecol. 2009 Jun.

Abstract

Magnesium sulfate has been used by obstetricians for more than 25 years to treat preterm labor. Magnesium sulfate is effective in delaying delivery for at least 48 hours in patients with preterm labor when used in higher dosages. There do not seem to be any harmful effects of the drug on the fetus, and indeed there is a neuroprotective effect in reducing the incidence of cerebral palsy in premature newborns weighing less than 1,500 g.

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Comment in

  • Evidence-based medicine under attack.
    Scott JR. Scott JR. Obstet Gynecol. 2009 Jun;113(6):1202-1203. doi: 10.1097/AOG.0b013e3181a72842. Obstet Gynecol. 2009. PMID: 19461412 No abstract available.

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References

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    1. Glock JL, Morales J. Efficacy and safety of nifedipine versus magnesium sulfate in the management of preterm labor: a randomized study. Am J Obstet Gynecol 1992;169:960–4.

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