Review
doi: 10.1039/b901287g.
Epub 2009 Apr 23.
Myxobacteria--'microbial factories' for the production of bioactive secondary metabolites
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- PMID: 19462013
- DOI: 10.1039/b901287g
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Review
Myxobacteria--'microbial factories' for the production of bioactive secondary metabolites
Mol Biosyst.
2009 Jun.
Abstract
In this article, we briefly review the potential of myxobacteria as 'natural product factories' by highlighting results from the recently sequenced myxobacterial model strain Myxococcus xanthus. We will focus on the production of polyketides, non-ribosomally-made peptides, and their hybrids, and discuss the evaluation of biosynthetic potential using genome-based methods, as well as biosynthetic process engineering.
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