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Comment
. 2009 May;30(5):666-8.
doi: 10.1016/j.immuni.2009.04.008.

The calculus of integrating differentiation: timing control of T-bet

Mark Boothby  1
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The calculus of integrating differentiation: timing control of T-bet

Mark Boothby. Immunity. 2009 May.
Free article

Abstract

In this issue of Immunity, Schulz et al. (2009) use mathematical modeling to elucidate a signaling network controlling Ifng gene expression, thereby showing the importance of an Interleukin-12-dependent, Interferon-gamma-independent second phase of inducing the transcription factor T-bet.

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