Photochemically induced transformation of adrenochrome to adrenochrome-melanin
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- PMID: 1946698
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Photochemically induced transformation of adrenochrome to adrenochrome-melanin
Physiol Chem Phys Med NMR.
1991.
Abstract
The photochemical decomposition of adrenochrome in aqueous and deuterated solutions by visible light was investigated. From the spectroscopic study the disappearance constant k = 4.8 x 10(-5) s-1 as well as quenching constant kq = 2.5 x 10(-1) [s M-1] and isotope effect kD/kH = 2 for singlet oxygen mechanism have been calculated. A possible chemical mechanism for the observed transformation of adrenochrome to the melanin polymer is discussed including the formation of the reactive intermediate species like cytotoxic quinones.
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