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. 2009 Jun;20(6):1175-8.
doi: 10.1681/ASN.2009030321. Epub 2009 May 21.

Common sense approaches to urinary biomarker study design

Mark A Knepper  1
Affiliations

Common sense approaches to urinary biomarker study design

Mark A Knepper. J Am Soc Nephrol. 2009 Jun.
No abstract available

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Figures

Figure 1.
Figure 1.
Workflow for urinary biomarker development studies.
See this image and copyright information in PMC

Comment in

References

    1. Knepper MA: Proteomics and the kidney. J Am Soc Nephrol 13: 1398–1408, 2002 - PubMed
    1. Thongboonkerd V, McLeish KR, Arthur JM, Klein JB: Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney Int 62: 1461–1469, 2002 - PubMed
    1. Pisitkun T, Shen RF, Knepper MA: Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci U S A 101: 13368–13373, 2004 - PMC - PubMed
    1. Adachi J, Kumar C, Zhang Y, Olsen JV, Mann M: The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins. Genome Biol 7: R80, 2006 - PMC - PubMed
    1. Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA: Large-scale proteomics and phosphoproteomics of urinary exosomes. J Am Soc Nephrol 20: 363–379, 2009 - PMC - PubMed

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