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. 2004 Jan 26;12(2):331-41.
doi: 10.1364/opex.12.000331.

Nonlinear optical contrast enhancement for optical coherence tomography

Claudio Vinegoni, Jeremy Bredfeldt, Daniel Marks, Stephen Boppart
Free article

Nonlinear optical contrast enhancement for optical coherence tomography

Claudio Vinegoni et al. Opt Express. .
Free article

Abstract

We present a new interferometric technique for measuring Coherent Anti-Stokes Raman Scattering (CARS) and Second Harmonic Generation (SHG) signals. Heterodyne detection is employed to increase the sensitivity in both CARS and SHG signal detection, which can also be extended to different coherent processes. The exploitation of the mentioned optical nonlinearities for molecular contrast enhancement in Optical Coherence Tomography (OCT) is presented.

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