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. 2009 Jun;80(6):882-8.

Marked increase in child survival after four years of intensive malaria control

Immo Kleinschmidt  1 , Christopher Schwabe, Luis Benavente, Miguel Torrez, Frances C Ridl, Jose Luis Segura, Paul Ehmer, Gloria Nseng Nchama
Affiliations

Marked increase in child survival after four years of intensive malaria control

Immo Kleinschmidt et al. Am J Trop Med Hyg. 2009 Jun.

Abstract

In malaria-endemic countries in Africa, a large proportion of child deaths are directly or indirectly attributable to infection with Plasmodium falciparum. Four years after high coverage, multiple malaria control interventions were introduced on Bioko Island, Equatorial Guinea, changes in infection with malarial parasites, anemia, and fever history in children were estimated and assessed in relation to changes in all-cause under-5 mortality. There were reductions in prevalence of infection (odds ratio [OR] = 0.31, 95% confidence interval [CI] = 0.2-0.46), anemia (OR = 0.11, 95% CI = 0.07-0.18), and reported fevers (OR = 0.41, 95% CI = 0.22-0.76) in children. Under-5 mortality fell from 152 per 1,000 births (95% CI = 122-186) to 55 per 1,000 (95% CI = 38-77; hazard ratio = 0.34 [95% CI = 0.23-0.49]). Effective malaria control measures can dramatically increase child survival and play a key role in achieving millennium development goals.

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Figures

Figure 1
Figure 1
Location of sentinel sites used to monitor the Bioko Island malaria control intervention, 2004 to 2008.
Figure 2
Figure 2
Timing of intervention activities and under five mortality surveys, Bioko, 2004 to 2008.
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References

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