Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Sep;137(1):9-17.
doi: 10.1007/s10709-009-9370-2. Epub 2009 May 29.

Mariner transposons as genetic tools in vertebrate cells

L Delaurière  1 , B Chénais, Y Hardivillier, L Gauvry, N Casse
Affiliations
Review

Mariner transposons as genetic tools in vertebrate cells

L Delaurière et al. Genetica. 2009 Sep.

Abstract

Transposable elements (TEs) are being investigated as potential molecular tools in genetic engineering, for use in procedures such as transgenesis and insertional mutagenesis. Naturally active and reconstructed active TEs are both being studied to develop non-viral delivery vehicles. To date, the active elements being used include three Mariner-Like Elements (MLEs). We review below the studies that have investigated the ability of these MLEs to insert a transgene in vertebrate cells.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):962-4 - PubMed
    1. Mol Biol Evol. 1995 May;12(3):421-31 - PubMed
    1. Reprod Biol Endocrinol. 2003 Nov 07;1:80 - PubMed
    1. Annu Rev Genet. 2002;36:389-410 - PubMed
    1. Nucleic Acids Res. 2003 Dec 1;31(23):6873-81 - PubMed

Publication types

LinkOut - more resources