Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2009 May;32(5):648-53.
doi: 10.1093/sleep/32.5.648.

Comparison of mandibular advancement splint and tongue stabilizing device in obstructive sleep apnea: a randomized controlled trial

Sheryn A Deane  1 , Peter A Cistulli, Andrew T Ng, Biao Zeng, Peter Petocz, M Ali Darendeliler
Affiliations
Randomized Controlled Trial

Comparison of mandibular advancement splint and tongue stabilizing device in obstructive sleep apnea: a randomized controlled trial

Sheryn A Deane et al. Sleep. 2009 May.

Erratum in

  • Sleep. 2009 Aug 1;32(8):table of contents

Abstract

Study objectives: To compare the efficacy of a mandibular advancement splint (MAS) and a novel tongue stabilizing device (TSD) in the treatment of obstructive sleep apnea (OSA).

Design: A randomized crossover design was used.

Patients: Twenty-seven patients (20 male, 7 female), recruited from a tertiary hospital sleep clinic.

Measurements and results: The apnea-hypopnea index (AHI) was reduced with MAS (11.68 +/- 8.94, P = 0.000) and TSD (13.15 +/- 10.77, P = 0.002) compared with baseline (26.96 +/- 17.17). The arousal index decreased for MAS (21.09 +/- 9.27, P = 0.004) and TSD (21.9 +/- 10.56, P = 0.001) compared with baseline (33.23 +/- 16.41). Sixty-eight percent of patients achieved a complete or partial response with MAS, compared with 45% with TSD. The Epworth Sleepiness Scale (ESS) score was decreased with MAS (P = < 0.001) and TSD (P = 0.002). Subjective improvements in snoring and quality of sleep were reported, with a better response for MAS than TSD. Compliance was poorer for TSD, and the side effect profiles of the 2 modalities were different. All patients were satisfied with MAS compared to TSD, and 91% of patients preferred the MAS.

Conclusion: Objective testing showed the MAS and TSD had similar efficacy in terms of AHI reduction. Patients reported improvements with both devices; however, better compliance and a clear preference for MAS was apparent when both devices were offered. Longer term studies are needed to clarify the role of TSD.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Schematic diagram summarizing the study design. PSG = polysomnography.
Figure 2
Figure 2
Photograph of upper and lower plates of the mandibular advancement splint.
Figure 3
Figure 3
Photograph of the tongue stabilizing device.
Figure 4
Figure 4
Comparison of compliance frequency reported by patients using MAS and TSD.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Cistulli P, Sullivan C, editors. In: Sleep and breathing. New York: Marcel Dekker Inc; 1994. Pathophysiology of sleep apnea.
    1. Anonymous. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement in clinical research. Sleep. 1999;22:667–89. - PubMed
    1. Qureshi A, Ballard RD. Obstructive sleep apnea. J Allergy Immunol. 2003;112:643–51. - PubMed
    1. Redline S. Epidemiology of sleep-disordered breathing. Semin Respir Crit Care Med. 1998;19:113–22.
    1. Ancoli-Israeli S, Kripke D, Klauber M, Mason W, Fell R, Kaplan O. Sleep-disordered breathing in community-dwelling elderly. Sleep. 1991;14:486–95. - PMC - PubMed

Publication types