Comment
doi: 10.1016/j.molcel.2009.05.004.
Keys to open chromatin for transcription activation: FACT and Asf1
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- PMID: 19481517
- DOI: 10.1016/j.molcel.2009.05.004
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Comment
Keys to open chromatin for transcription activation: FACT and Asf1
Mol Cell.
.
Free article
Abstract
In this issue of Molecular Cell, Takahata et al. (2009) dissect the mechanisms preceding transcription initiation, revealing a wave of nucleosome eviction, which spreads from distant cis-regulatory elements to promoters and which requires the activity of histone chaperones, FACT and Asf1.
Comment on
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FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter.Mol Cell. 2009 May 14;34(4):405-15. doi: 10.1016/j.molcel.2009.04.010. Mol Cell. 2009. PMID: 19481521 Free PMC article.
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