Related mechanisms for mRNA and rRNA quality control
- PMID: 19481519
- DOI: 10.1016/j.molcel.2009.05.008
Related mechanisms for mRNA and rRNA quality control
Abstract
In this issue of Molecular Cell, Cole et al. (2009) provide evidence that different defects in rRNA function are recognized by distinct RNA quality control systems, and suggest that a stalled ribosome can trigger either no-go decay of the mRNA or degradation of a nonfunctional 18S rRNA.
Comment on
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A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay.Mol Cell. 2009 May 14;34(4):440-50. doi: 10.1016/j.molcel.2009.04.017. Mol Cell. 2009. PMID: 19481524 Free PMC article.
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A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay.Mol Cell. 2009 May 14;34(4):440-50. doi: 10.1016/j.molcel.2009.04.017. Mol Cell. 2009. PMID: 19481524 Free PMC article.
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