Psammomatoid ossifying fibroma with secondary aneurysmal bone cyst of frontal sinus

Abstract

Introduction: Psammomatoid ossifying fibroma (POF) is a rare, slowly progressive tumor of the extragnathic craniofacial bones, with a tendency toward locally aggressive behavior.

Case report: The pathognomonic histologic feature is the presence of spherical ossicles, which are similar to psammoma bodies.

Discussion: Fibro-osseous lesions composed of POF and aneurysmal bone cyst (ABC) of the frontal sinus in a 12-year-old boy is reported, followed by a literature review.

Conclusion: To our knowledge, this is the second case of a fibro-osseous lesion composed of ossifying fibroma with reactive ABC to be reported in the literature.

Fig. 1

Preoperative CT scan brain axial views

Fig. 2

a Preoperative (plain) MRI brain T1 WI axial view. b Preoperative contrasted MRI T1 axial view

Fig. 3

3D CT scan of skull showing destroyed left supraorbital bone

Fig. 4

Post operative CT scan brain

Fig.5

Microscopic view shows calcified ossicles resemble psammoma bodies

Fig.6

Immunohistochemically, cells showed strong and diffuse reactivity for vimentin

Fig.7

No immunoreactivity for EMA

Fig.8

Large vascular spaces