Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jan-Feb;75(1):111-5.
doi: 10.1016/s1808-8694(15)30841-7.

A study on otoacoustic emissions and supression effects in patients with vitiligo

Affiliations

A study on otoacoustic emissions and supression effects in patients with vitiligo

Rosanna Mariangela Giaffredo Angrisani et al. Braz J Otorhinolaryngol. 2009 Jan-Feb.

Abstract

Vitiligo is a skin disease characterized by absence of melanin due to melanocytes destruction.

Aim: to study the incidence of hearing alterations in patients with vitiligo.

Method: prospective audiological evaluation, transient-evoked otoacoustic emission recordings and study the effects of suppression in 24 patients with vitiligo. Their ages ranged from 15 to 45 years.

Results: 21 patients (87.5%) had normal audiometry; 2 had unilateral hearing loss in the high frequencies and 1 had cochlear moderate hearing loss in the left ear. Of these 21 subjects, 66.7% had no otoacoustic emissions, suggesting cochlear dysfunction. Only 7 patients had otoacoustic emissions present in all frequencies (29.2%) and 17 (70.8%) did not have them, and the highest rate of no otoacoustic emissions happened in the right ear of males. Regarding the suppression study, 6 subjects failed, all of them were females, and their left ears were the most affected.

Conclusion: the findings show that patients with vitiligo, particularly males, have a greater predisposition to cochlear dysfunction, especially in the right ear. As far as the suppression effect was concerned, there was a greater alteration in the female efferent system, particularly in the left ear. Hearing alterations did not vary as far as age is concerned, type of vitiligo and time of disease progression.

PubMed Disclaimer

References

    1. Nordlund JJ, Majumder PP. Recent investigations on vitiligo vulgaris: advances in clinical research. Dermatol Clin. 1997;15:69–78. - PubMed
    1. Steiner D, et al. Vitiligo An Bras Dermatol. Rio de Janeiro. 2004;79(3) Disponívelem: Acesso em: 09 July 2007. Pré-publicação.
    1. Savin MSC. The blood vessels and Pigmentary Cells of the Inner Ear. Ann Otol Rhinol Laryngol. 1965;74:611–623. - PubMed
    1. LaFerriere KA, Arenberg IK, Hawkins Junior JE, Johnsson LG. Melanocytes of the Vestibular Labyrinth and their Relantionship to the Microvasculature. Ann Otol. 1974;83:685–694. - PubMed
    1. Franz P, Aharinejad S, Firbas W. Melanocytes in the Modiolus of Guinea Pig Coclea. Acta Otolaryngol (Stockh). 1990;109:221–227. - PubMed