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Practice Guideline
. 2009 Jul 1;49(1):1-45.
doi: 10.1086/599376.

Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America

Leonard A Mermel  1 , Michael Allon, Emilio Bouza, Donald E Craven, Patricia Flynn, Naomi P O'Grady, Issam I Raad, Bart J A Rijnders, Robert J Sherertz, David K Warren
Affiliations
Practice Guideline

Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America

Leonard A Mermel et al. Clin Infect Dis. .

Erratum in

  • Clin Infect Dis. 2010 Apr 1;50(7):1079. Dosage error in article text
  • Clin Infect Dis. 2010 Feb 1;50(3):457

Abstract

These updated guidelines replace the previous management guidelines published in 2001. The guidelines are intended for use by health care providers who care for patients who either have these infections or may be at risk for them.

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Conflict of interest statement

Potential conflicts of interest. L.A.M. has received research funding from Angiotech and Theravance and has served as a consultant to Cadence, Ash Access Technology, and CorMedix. M.A. is a consultant for Angiotech and Covidien. E.B. has served on advisory boards for or received research or conference funds from Pfizer, Merck Sharp and Dohme, Cerexa, Cardinal-Health, Sanofi-Aventis, GlaxoSmithKline, Astellas and Astra-Zeneca. D.E.C. has served on the speaker’s bureaus of Pfizer, Wyeth, Sanofi Pasteur, and Merck and has received research funding from Bard, Nomir Medical Technologies, Data and Safety Monitoring Board, and Johnson & Johnson. B.J.A.R. has received research grants from Schering-Plough and Gilead Sciences; has served as a speaker for Bayer, Schering-Plough, Pfizer, and Tibotec; and has served as a consultant to Pfizer and Schering-Plough. P.F. has clinical research contracts with MedImmune and Tibotec. I.I.R. has received research grants from Cubist, Schering-Plough, Versicor, Enzon, Cook Medical, Schering-Plough, and Wyeth; has served on the speaker bureaus of Merck, Pfizer, Cook, and Schering-Plough; has served as a consultant to Clorox, Cubist, and Cook; and has received royalties related to patent licensed to American Medical Systems, Horizon Medical Products, and TyRx on which he is a coinventor. D.K.W. has served on the Pfizer speaker’s bureau; has received research funding from GeneOhm Sciences, Verimetrix, and Astellas Pharma; and has served as a consultant to 3M Healthcare. N.P.O. and R.J.S.: no conflicts.

Figures

Figure 1
Figure 1
Approach to the management of patients with short-term central venous catheter–related or arterial catheter–related bloodstream infection. CFU, colony-forming units; S. aureus, Staphylococcus aureus.
Figure 2
Figure 2
Catheter-related blood stream infection (CRBSI) among patients who are undergoing hemodialysis (HD) with tunneled catheters. BC, blood culture; CVC, central venous catheter; TEE, transesophageal echocardiograph.
Figure 3
Figure 3
Methods for the diagnosis of acute fever for a patient suspected of having short-term central venous catheter infection or arterial catheter infection. CFU, colony-forming units.
Figure 4
Figure 4
Approach to the treatment of a patient with a long-term central venous catheter (CVC) or a port (P)-related bloodstream infection.
See this image and copyright information in PMC

Comment in

References

    1. Mermel LA, Farr BM, Sherertz RJ, et al. Guidelines for the management of intravascular catheter-related infections. Clin Infect Dis. 2001;32:1249–72. - PubMed
    1. Field MJ, Lohr KN, editors. Institute of Medicine Committee to Advise the Public Health Service on Clinical Practice Guidelines. Clinical practice guidelines: directions for a new program. Washington, DC: National Academy Press; 1990. - PubMed
    1. The periodic health examination. Canadian Task Force on the Periodic Health Examination. Can Med Assoc J. 1979;121:1193–254. - PMC - PubMed
    1. Maki DG, Mermel LA. Infections due to infusion therapy. In: Bennett JV, Brachman PS, editors. Hospital infections. Philidelphia, PA: Lippincott-Raven; 1998. pp. 689–724.
    1. Mermel LA. Prevention of intravascular catheter-related infections. Ann Intern Med. 2000;132:391–402. - PubMed

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