Congenital gastrointestinal anomalies in anorectal malformations: what relationship and management?

Abstract

To date, no systematic review of gastrointestinal anomalies associated with anorectal malformations has been performed. We report the management of three challenging cases of neonates affected by congenital gastrointestinal and anorectal malformations and we review the pertinent published reports to disclose the incidence and outcome of this combination. In 3951 anorectal malformations, the incidence of digestive tract anomalies was approximately 15%. The association of multiple congenital gastrointestinal defects strongly increased the case complexity and worsened the outcome. Based on our study, the application of a rational and staged management plan provides easier diagnosis and treatment of complex cases. Moreover, keeping in mind the likely co-occurrence of anorectal and gastrointestinal anomalies could help avoid misdiagnosis and prevent life-threatening complications. Finally, the knowledge of this association and its successful management can help the multi-specialist team to become more confident in counselling, diagnosis and treatment.