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Case Reports
. 2009 Nov;54(5):931-4.
doi: 10.1053/j.ajkd.2009.03.013. Epub 2009 Jun 3.

Fanconi syndrome due to deferasirox

Cédric Rafat  1 , Fadi Fakhouri, Jean-Antoine Ribeil, Richard Delarue, Moglie Le Quintrec
Affiliations
Case Reports

Fanconi syndrome due to deferasirox

Cédric Rafat et al. Am J Kidney Dis. 2009 Nov.

Abstract

Deferasirox is an innovative iron-chelating treatment. However, preliminary data have suggested that kidney toxicity may be a major issue in the management of patients receiving this drug. We report a case of Fanconi syndrome associated with acute renal insufficiency in a patient receiving deferasirox. The latter has to be added to the expanding list of drugs that may induce Fanconi syndrome. Careful monitoring of kidney function and markers of proximal tubular injury are mandatory in patients undergoing treatment with deferasirox.

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