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Case Reports
. 2009 Jun 7;15(21):2669-71.
doi: 10.3748/wjg.15.2669.

Ceftriaxone-induced toxic hepatitis

Erdal Peker  1 , Eren Cagan, Murat Dogan
Affiliations
Case Reports

Ceftriaxone-induced toxic hepatitis

Erdal Peker et al. World J Gastroenterol. .

Abstract

Toxic hepatitis or drug-induced liver injury encompasses a spectrum of clinical disease ranging from mild biochemical abnormalities to acute liver failure. The advantages of a long half-life, wide spectrum, high tissue penetration rate, and a good safety profile, make ceftriaxone, a third-generation cephalosporin, a frequent choice in the treatment of childhood infections. Previous studies have reported a few cases of high aspartate aminotransferase and alanine aminotransferase levels, along with three cases of hepatitis caused by ceftriaxone. Here, we report a case of drug-induced toxic hepatitis in a patient who was treated with ceftriaxone for acute tonsillitis.

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