Neuropsychiatric disorders: The choice of antipsychotics in schizophrenia
- PMID: 19498434
- DOI: 10.1038/nrneurol.2009.68
Neuropsychiatric disorders: The choice of antipsychotics in schizophrenia
Abstract
In light of claims of improved efficacy and lower incidence of adverse effects compared with older drugs, second-generation antipsychotics have emerged as the predominant treatment for schizophrenia. A new meta-analysis concludes that the difference in efficacy between newer and older agents is small, and the current classification scheme for antipsychotics does not survive close scrutiny.
Comment on
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Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis.Lancet. 2009 Jan 3;373(9657):31-41. doi: 10.1016/S0140-6736(08)61764-X. Epub 2008 Dec 6. Lancet. 2009. PMID: 19058842
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