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Randomized Controlled Trial
. 2009 Jun 8:9:16.
doi: 10.1186/1472-6874-9-16.

The effects of postmenopausal hormone therapy on social activity, partner relationship, and sexual life - experience from the EPHT trial

Elina Hemminki  1 , Piret Veerus, Heti Pisarev, Sirpa-Liisa Hovi, Päivi Topo, Helle Karro
Affiliations
Randomized Controlled Trial

The effects of postmenopausal hormone therapy on social activity, partner relationship, and sexual life - experience from the EPHT trial

Elina Hemminki et al. BMC Womens Health. .

Abstract

Background: With the exception of sexual functioning and weight, social and behavioural effects of postmenopausal hormone therapy (HT) have not been reported from trials. This paper reports such results from the EPHT-trial in Estonia.

Methods: A randomized trial, with a blind and non-blind sub-trial in Estonia. From 1999-2001, 1778 women were recruited. The mean follow-up was 3.6 years. Women's experiences were asked in the first and final study year by mailed questionnaires (74 and 81% response rates). Comparisons of the groups were made by cross-tabulation and logistic regression, adjusting for age.

Results: There were no differences between the HT and non-HT groups in regard to being employed, the extent of social involvement or marital status or opinions on aging. There was no difference in the frequency of free-time exercise, or overweight. Some of the indicators suggested less sexual inactivity, but the differences were small.

Conclusion: In a trial setting, postmenopausal hormone therapy did not influence work or social involvement or health behaviour.

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References

    1. Topo P. Climacteric hormone therapy in medical and lay texts in Finland from 1955 to 1992. Soc Sci Med. 1997;45:751–760. doi: 10.1016/S0277-9536(96)00411-X. - DOI - PubMed
    1. Siegel Watkins E. The estrogen elixir A history of hormone replacement therapy in America. Baltimore: The Johns University Press; 2007.
    1. Nilsen ST, Pedersen AT, Moen MH, Milsom I, Mattsson LA, Iversen OE, Larsen PM, Andersson K. Knowledge, attitudes and management strategies in Scandinavia concerning hormone replacement therapy. A comparison between gynecologists in Denmark, Norway and Sweden. Maturitas. 2001;39:83–90. doi: 10.1016/S0378-5122(01)00187-6. - DOI - PubMed
    1. Baron J, Holzman GB, Schulkin J. Attitudes of Obstetricians and Gynecologists toward Hormone Replacement Therapy. Psychol Decis Making. 1998;18:406–411. doi: 10.1177/0272989X9801800408. - DOI - PubMed
    1. Hemminki E, Topo P. Prescribing hormone therapy in menopause and postmenopause. J Psychosom Obstet Gynecol. 1997;18:145–157. doi: 10.3109/01674829709085581. - DOI - PubMed

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