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Randomized Controlled Trial
. 2010 Jan;83(985):35-9.
doi: 10.1259/bjr/23203690. Epub 2009 Jun 8.

Reduction of the total injection volume of contrast material with a short injection duration in 64-detector row CT coronary angiography

F Tatsugami  1 , T Kanamoto, G Nakai, Y Takeda, H Morita, I Morinaga, S Yoshikawa, I Narabayashi
Affiliations
Randomized Controlled Trial

Reduction of the total injection volume of contrast material with a short injection duration in 64-detector row CT coronary angiography

F Tatsugami et al. Br J Radiol. 2010 Jan.

Abstract

The ability of short injection duration of contrast material to reduce the total injection volume in 64-detector row CT coronary angiography was investigated. 45 patients were divided into three groups: (i) those receiving 0.8 ml kg(-1) of contrast material (350 mgI ml(-1)) injected with a fixed duration of 14 s (Group A; n = 16); (ii) those receiving 0.8 ml kg(-1) of contrast material injected with a fixed duration of 10 s (Group B; n = 15); and (iii) those receiving 0.7 ml kg(-1) of contrast material injected with a fixed duration of 10 s (Group C; n = 14). All patients then received 20 ml of saline. Contrast densities of the ascending aorta and proximal and distal coronary arteries were assessed where vessel diameters were >2.0 mm. The mean enhancement value in the ascending aorta for Group B was significantly higher than that for Groups A and C (p<0.05), whereas there was no significant difference between Groups A and C. All enhancement values in the coronary arteries were higher than 250 Hounsfield units. The mean enhancement value for each coronary artery in Group B was significantly higher than that for Group A (p<0.05), whereas there was no significant difference between Groups A and C. In conclusion, a short injection duration allows a reduction in the total volume of contrast material from 0.8 ml kg(-1) to 0.7 ml kg(-1) while a steady contrast enhancement is maintained in the ascending aorta and coronary arteries.

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Figures

Figure 1
Figure 1
(a,b) Enhancement values for the ascending aorta (black line), right ventricular outflow tract (white line), right ventricle (dotted white line) and left ventricle (dotted black line) were measured using a circular region of interest cursor.
Figure 2
Figure 2
Enhancement values for each coronary artery segment were measured on the cross-sectional images using a circular region of interest cursor (dotted line). Ao, aorta; LAD, left anterior descending artery.
Figure 3
Figure 3
The mean enhancement values for each coronary artery segment.
See this image and copyright information in PMC

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