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. 2009 Aug;53(8):3552-60.
doi: 10.1128/AAC.00418-09. Epub 2009 Jun 8.

Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria

Wolfgang Haas  1 , Chris M Pillar, Gary E Zurenko, Jacqueline C Lee, Lynne S Brunner, Timothy W Morris
Affiliations

Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria

Wolfgang Haas et al. Antimicrob Agents Chemother. 2009 Aug.

Abstract

The antibacterial spectrum of besifloxacin, a novel fluoroquinolone recently approved for treatment of ocular infections, was studied using 2,690 clinical isolates representing 40 species. Overall, besifloxacin was the most potent agent tested against gram-positive pathogens and anaerobes and was generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrated potent, broad-spectrum activity, which was particularly notable against gram-positive and gram-negative isolates that were resistant to other fluoroquinolones and classes of antibacterial agents.

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Figures

FIG. 1.
FIG. 1.
Chemical structure of besifloxacin hydrochloride.
See this image and copyright information in PMC

References

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