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Comment
. 2009 Jun 16;106(24):E62; author reply E63.
doi: 10.1073/pnas.0904068106. Epub 2009 Jun 8.

Xq28 and lupus: IRAK1 or MECP2?

Amr H Sawalha
Comment

Xq28 and lupus: IRAK1 or MECP2?

Amr H Sawalha. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: A.H.S. is listed as an inventor on the patent filed by the Oklahoma Medical Research Foundation for the discovery of MECP2's association with lupus.

Comment on

  • Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
    Jacob CO, Zhu J, Armstrong DL, Yan M, Han J, Zhou XJ, Thomas JA, Reiff A, Myones BL, Ojwang JO, Kaufman KM, Klein-Gitelman M, McCurdy D, Wagner-Weiner L, Silverman E, Ziegler J, Kelly JA, Merrill JT, Harley JB, Ramsey-Goldman R, Vila LM, Bae SC, Vyse TJ, Gilkeson GS, Gaffney PM, Moser KL, Langefeld CD, Zidovetzki R, Mohan C. Jacob CO, et al. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6256-61. doi: 10.1073/pnas.0901181106. Epub 2009 Mar 27. Proc Natl Acad Sci U S A. 2009. PMID: 19329491 Free PMC article.

References

    1. Sawalha AH, et al. Common variants within MECP2 confer risk of systemic lupus erythematosus. PLoS ONE. 2008;3:e1727. - PMC - PubMed
    1. Jacob CO, et al. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci USA. 2009;106:6256–6261. - PMC - PubMed
    1. Chahrour M, et al. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science. 2008;320:1224–1229. - PMC - PubMed
    1. Urdinguio RG, et al. Mecp2-null mice provide new neuronal targets for Rett syndrome. PLoS ONE. 2008;3:e3669. - PMC - PubMed

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