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Case Reports
. 1991 Oct 1;41(1):112-4.
doi: 10.1002/ajmg.1320410127.

PCR detection of distal Yp sequences in an XX true hermaphrodite

Y Nakagome  1 , S Seki, K Fukutani, S Nagafuchi, Y Nakahori, T Tamura
Affiliations
Case Reports

PCR detection of distal Yp sequences in an XX true hermaphrodite

Y Nakagome et al. Am J Med Genet. .

Abstract

An XX true hermaphrodite was examined for the presence of Y-specific sequences using Southern-blotting and polymerase chain reaction (PCR) techniques. Of 25 loci examined, only two, the proximal border of the pseudoautosomal region (PABY) and the sex determining region of the Y chromosome (SRY), were detected. A crossing over event in paternal meiosis, proximal to the SRY locus but distal to the zinc finger protein (ZFY) locus, presumably transferred to two loci to the X chromosome.

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