Retinoblastoma, an inside job
- PMID: 19524501
- DOI: 10.1016/j.cell.2009.05.034
Retinoblastoma, an inside job
Abstract
Why are some cell types more prone to transformation than others? In this issue, Xu et al. (2009) show that retinoblastoma cells co-opt several intrinsic features of cone photoreceptors for their survival and growth.
Comment on
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Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling.Cell. 2009 Jun 12;137(6):1018-31. doi: 10.1016/j.cell.2009.03.051. Cell. 2009. PMID: 19524506 Free PMC article.
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