doi: 10.1126/science.195342.
Three hypolipidemic drugs increase hepatic palmitoyl-coenzyme A oxidation in the rat
- PMID: 195342
- DOI: 10.1126/science.195342
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Three hypolipidemic drugs increase hepatic palmitoyl-coenzyme A oxidation in the rat
Science.
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Abstract
Male rats treated with clofibrate, tibric acid, or Wy-14,643 show an 11- to 18-fold increase in the capacity of their livers to oxidize palmitoyl-coenzyme A. This provides a plausible biochemical mechanism for the action of these hypolipidemic drugs in reducing lipid concentrations in the serum.
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