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Case Reports
. 2009 Sep;4(3):207-8.
doi: 10.2174/157488609789007001. Epub 2009 Sep 1.

A case of topiramate-induced epistaxis

Giovanni Polimeni  1 , Rosario Grugno, Antongiulio Vitetta, Francesco Cordici, Antonella Alagna, Achille P Caputi, Placido Bramanti
Affiliations
Case Reports

A case of topiramate-induced epistaxis

Giovanni Polimeni et al. Curr Drug Saf. 2009 Sep.

Abstract

The current case describes epistaxis in a patient treated with a daily regimen of topiramate 100mg for migraine. The patient had not a past medical history of nosebleeds and laboratory parameters were within normal ranges. She was then advised to withdraw topiramate, and the epistaxis resolved within 12 hours after its discontinuation. Since then, the patient never complained other blood clotting disorders. The potential antiplatelet activity of topiramate is discussed.

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