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Comment
. 2009 Aug;297(2):C227-30.
doi: 10.1152/ajpcell.00256.2009. Epub 2009 Jun 17.

A new role for satellite cells: control of reinnervation after muscle injury by semaphorin 3A. Focus on "Possible implication of satellite cells in regenerative motoneuritogenesis: HGF upregulates neural chemorepellent Sema3A during myogenic differentiation"

Linda K McLoon  1
Affiliations
Comment

A new role for satellite cells: control of reinnervation after muscle injury by semaphorin 3A. Focus on "Possible implication of satellite cells in regenerative motoneuritogenesis: HGF upregulates neural chemorepellent Sema3A during myogenic differentiation"

Linda K McLoon. Am J Physiol Cell Physiol. 2009 Aug.
No abstract available

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Figures

Fig. 1.
Fig. 1.
Model of a single myofiber before and after injury. A: a single myofiber (orange) is surrounded by a basal lamina (black). Quiescent satellite cells (blue) are located in the space (cream) between the basal lamina (black) and the sarcolemma of the myofiber. A single axon forms a neuromuscular junction in the central region of this fiber (yellow). The myofibers are surrounded by intact blood vessels, depicted here as strands (red). B: after injury, the myofiber begins to necrose and die (brick red). Initially, hepatocyte growth factor (HGF, pink) is released into the space between the basal lamina (black) and the sarcolemma, activating the satellite cells (green). Within 48 h, the activated satellite cells secrete semaphorin 3A (purple), which in postulated to repel in-growing neurites (yellow) and cause blood vessel remodeling (red).
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References

    1. Acevedo LM, Barillas S, Weis SM, Goethert JR, Cheresh DA. Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor. Blood 111: 2674–2680, 2008 - PMC - PubMed
    1. Allen RE, Boxhorn LK. Regulation of skeletal muscle satellite cell proliferation and differentiation by transforming growth factor-beta, insulin-like growth factor I and fibroblast growth factor. J Cell Physiol 138: 311–315, 1989 - PubMed
    1. Allen RE, Dodson MV, Luiten LS. Regulation of skeletal muscle satellite cell proliferation by bovine pituitary fibroblast growth factor. Exp Cell Res 152: 154–160, 1984 - PubMed
    1. Allen RE, Sheehan SM, Taylor RG, Kendall TL, Rice GM. Hepatocyte growth factor activates quiescent skeletal muscle satellite cells in vitro. J Cell Physiol 165: 307–312, 1995 - PubMed
    1. Anderson JE. A role for nitric oxide in muscle repair: nitric oxide-mediated activation of muscle satellite cells. Mol Biol Cell 11: 1859–1874, 2000 - PMC - PubMed

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