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Review
. 2009 Jul-Aug;6(3):335-40.
doi: 10.4161/rna.6.3.9013. Epub 2009 Jul 14.

Micromanipulating cancer: microRNA-based therapeutics?

Fabio Petrocca  1 , Judy Lieberman
Affiliations
Free article
Review

Micromanipulating cancer: microRNA-based therapeutics?

Fabio Petrocca et al. RNA Biol. 2009 Jul-Aug.
Free article

Abstract

Because microRNAs regulate cancer cell differentiation, proliferation, survival and metastasis, manipulating microRNA function, either by mimicking or inhibiting miRNAs implicated in cancer, could provide a powerful therapeutic strategy to interfere with key pathways for cancer progression. This review will explore some of the opportunities and obstacles to harnessing microRNA biology for cancer therapy.

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