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Comment
. 2009 Jun 19;30(6):759-61.
doi: 10.1016/j.immuni.2009.06.002.

m(en)TOR(ing) differentiating T helper cells

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m(en)TOR(ing) differentiating T helper cells

I-Cheng Ho. Immunity. .
Free article

Abstract

The decision of naive Th cells to assume the fate of effector or regulator Th cells heavily influences the outcome of adaptive immune responses. In this issue of Immunity, Delgoffe et al. (2009) use genetic approaches and demonstrate that mTOR kinase plays a critical role in this decision-making process.

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