m(en)TOR(ing) differentiating T helper cells
- PMID: 19538925
- DOI: 10.1016/j.immuni.2009.06.002
m(en)TOR(ing) differentiating T helper cells
Abstract
The decision of naive Th cells to assume the fate of effector or regulator Th cells heavily influences the outcome of adaptive immune responses. In this issue of Immunity, Delgoffe et al. (2009) use genetic approaches and demonstrate that mTOR kinase plays a critical role in this decision-making process.
Comment on
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The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.Immunity. 2009 Jun 19;30(6):832-44. doi: 10.1016/j.immuni.2009.04.014. Immunity. 2009. PMID: 19538929 Free PMC article.
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