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Review
. 2010 Jan;9(3):153-7.
doi: 10.1016/j.autrev.2009.06.001. Epub 2009 Jun 16.

Pregnancy, postpartum autoimmune thyroiditis, and autoimmune hypophysitis: intimate relationships

Melissa A Landek-Salgado  1 , Angelika Gutenberg, Isabella Lupi, Hiroaki Kimura, Stefano Mariotti, Noel R Rose, Patrizio Caturegli
Affiliations
Review

Pregnancy, postpartum autoimmune thyroiditis, and autoimmune hypophysitis: intimate relationships

Melissa A Landek-Salgado et al. Autoimmun Rev. 2010 Jan.

Abstract

Autoimmune diseases comprise a group of about 85 heterogeneous conditions that can affect virtually any organ and tissue in the body. Many autoimmune diseases change significantly during pregnancy: some ameliorate, some worsen, and others are unaffected. Two autoimmune diseases present prominently in relation to pregnancy: postpartum autoimmune thyroiditis and autoimmune hypophysitis. This article will review the current state of knowledge of the immunological changes that occur during normal pregnancy, and will explore the striking temporal association with pregnancy observed in thyroiditis and hypophysitis.

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Figure 1
Figure 1
Serum levels of pituitary (A) and placental (B) hormones during pregnancy.
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