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. 2009 Jun;3(3):E4-E6.
doi: 10.5489/cuaj.1088.

A case of metastatic adenocarcinoma of the prostate arising in a meningioma

Devin Pugsley  1 , Greg Bailly, Rekha Gupta, Derek Wilke, Lori Wood
Affiliations

A case of metastatic adenocarcinoma of the prostate arising in a meningioma

Devin Pugsley et al. Can Urol Assoc J. 2009 Jun.

Abstract
in English, French

We present the case of a 70-year-old man who had a prostate adenocarcinoma that metastatized to a previously unknown cranial meningioma. Central nervous system (CNS) metastases are very uncommon in patients with prostate cancer, and metastases to pre-existing primary CNS tumours are even more uncommon. Rare events like this can cause diagnostic uncertainty, as shown by this case. This case is a reminder for clinicians to consider prostate metastases in patients with known prostate carcinoma and focal neurological symptoms.

Nous décrivons le cas d'un homme de 70 ans présentant un adénocarcinome métastatique de la prostate secondaire à un méningiome intracrânien non diagnostiqué auparavant. Les métastases au niveau du SNC sont très rares chez les patients atteints de cancer de la prostate et les métastases sont encore plus rares dans le cas de tumeurs primitives pré-existantes au niveau du SNC. La rareté de ces cas peut soulever des incertitudes au niveau du diagnostic, comme nous le montrerons. Ce cas permet de rappeler aux cliniciens d'envisager la possibilité de métastases chez les patients atteints d'un carcinome prostatique confirmé et présentant des signes neurologiques focaux.

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Figures

Fig. 1.
Fig. 1.
Computed tomography scan showing an 8.3-cm right parietal dural lesion with midline shift.
Fig. 2.
Fig. 2.
T1-weighted magnetic resonance image showing marked decrease in the parietal dural–based lesion following treatment with dexamethasone.
Fig. 3.
Fig. 3.
Hematoxylin–eosin stain showing both meningothelial meningioma and metastatic prostate carcinoma (original magnification × 200).
Fig. 4.
Fig. 4.
Prostate-specific antigen stain showing metastatic prostate adenocarcinoma cells (original magnification × 200).
See this image and copyright information in PMC

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