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Review
. 2009 Feb;28(2):184-7.
Epub 2009 Feb 12.

Interaction of indoleamine-2,3-dioxyagnase and CD4+CD25+ regulatory T cells in tumor immune escape

Hui Wang  1 , Ke Pan, Jian-Chuan Xia
Affiliations
  • PMID: 19550135
Free article
Review

Interaction of indoleamine-2,3-dioxyagnase and CD4+CD25+ regulatory T cells in tumor immune escape

Hui Wang et al. Ai Zheng. 2009 Feb.
Free article

Abstract

There are numerous factors involved in the tumor evasion from immune surveillance. Recently, considerable attention has been given to indoleamine 2,3-dioxygenase (IDO) and CD4(+)CD25(+) regulatory T cells (Tregs). The interaction between the two may play a crucial role in tumor immune escape. This article reviews the correlation between IDO and Tregs in immune escape of tumors.

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