Spatio-temporal control of cell coculture interactions on surfaces
- PMID: 19551797
- DOI: 10.1002/cbic.200900277
Spatio-temporal control of cell coculture interactions on surfaces
Abstract
Coculture control: We report a combined photochemical and electroactive self-assembled monolayer (SAM)-based substrate strategy to generate a coculture platform with spatial and temporal control of cell-cell interactions. These dynamic substrates can present a variety of ligands on the surface for biospecific interactions between the ligands and cell surface receptors. Photopatterning enables the ligands to be immobilized in patterns and even gradients.
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