Adenovirus type 3 outbreak in connecticut associated with a novel variant
- PMID: 19551823
- PMCID: PMC2897138
- DOI: 10.1002/jmv.21539
Adenovirus type 3 outbreak in connecticut associated with a novel variant
Abstract
An adenovirus outbreak occurred in New Haven, Connecticut in 2006-2007. Molecular typing revealed a twofold increase in adenovirus type 3 infections. Restriction enzyme analysis (REA) indicated that the CT outbreak was largely due to a marked increase in the novel Ad3a51 strain. This outbreak represents the first detection of Ad3a51 in the United States. While most infections were mild, children under 3 were at increased risk for severe disease and one patient with underlying disease died.
2009 Wiley-Liss, Inc.
Conflict of interest statement
Conflict of interest: Gregory C. Gray serves on the data monitoring board for adenovirus vaccine trials sponsored by Duramed.
All other authors: no conflicts.
Marie L. Landry, No conflict
Mark G. Lebeck, No conflict
Ana W. Capuano, No conflict
Troy McCarthy, No conflict
Figures
References
-
- Barker JH, Luby JP, Sean Dalley A, Bartek WM, Burns DK, Erdman DD. Fatal type 3 adenoviral pneumonia in immunocompetent adult identical twins. Clin Infect Dis. 2003;37(10):e142–146. - PubMed
-
- Brummitt CF, Cherrington JM, Katzenstein DA, Juni BA, Van Drunen N, Edelman C, Rhame FS, Jordan MC. Nosocomial adenovirus infections: molecular epidemiology of an outbreak due to adenovirus 3a. J Infect Dis. 1988;158(2):423–432. - PubMed
-
- Chang SY, Lee CN, Lin PH, Huang HH, Chang LY, Ko W, Chang SF, Lee PI, Huang LM, Kao CL. A community-derived outbreak of adenovirus type 3 in children in Taiwan between 2004 and 2005. J Med Virol. 2008;80(1):102–112. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
