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. 2009 Aug;81(8):1380-4.
doi: 10.1002/jmv.21539.

Adenovirus type 3 outbreak in connecticut associated with a novel variant

Affiliations

Adenovirus type 3 outbreak in connecticut associated with a novel variant

Marie L Landry et al. J Med Virol. 2009 Aug.

Abstract

An adenovirus outbreak occurred in New Haven, Connecticut in 2006-2007. Molecular typing revealed a twofold increase in adenovirus type 3 infections. Restriction enzyme analysis (REA) indicated that the CT outbreak was largely due to a marked increase in the novel Ad3a51 strain. This outbreak represents the first detection of Ad3a51 in the United States. While most infections were mild, children under 3 were at increased risk for severe disease and one patient with underlying disease died.

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Conflict of interest statement

Conflict of interest: Gregory C. Gray serves on the data monitoring board for adenovirus vaccine trials sponsored by Duramed.

All other authors: no conflicts.

Marie L. Landry, No conflict

Mark G. Lebeck, No conflict

Ana W. Capuano, No conflict

Troy McCarthy, No conflict

Figures

Fig. 1
Fig. 1
Total number of adenovirus-positive clinical specimens (bar), with all adenovirus type 3 (solid line), variant Ad3a50 and variant Ad3a51 positive specimens (dotted lines), Clinical Virology Laboratory, Department of Laboratory Medicine, Yale New Haven Hospital, New Haven, Connecticut, July 2004 to April 2007.

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