Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2009 May-Jun;31(3):1-10.

An intervention to improve cancer patients' understanding of early-phase clinical trials

Nancy E Kass  1 , Jeremy Sugarman, Amy M Medley, Linda A Fogarty, Holly A Taylor, Christopher K Daugherty, Mark R Emerson, Steven N Goodman, Fay J Hlubocky, Herbert I Hurwitz, Michael Carducci, Annallys Goodwin-Landher
Affiliations
Randomized Controlled Trial

An intervention to improve cancer patients' understanding of early-phase clinical trials

Nancy E Kass et al. IRB. 2009 May-Jun.
No abstract available

PubMed Disclaimer

References

    1. Riecken HW, Ravich R. Informed consent to biomedical research in veterans administration hospitals. JAMA. 1982;248:344–348. - PubMed
    2. Rodenhuis S, Van Den Heuvel WJA, Annyas AA, et al. Patient motivation and informed consent in a phase I study of an anticancer agentEuropean Journal of Cancer and Clinical Oncology 198420457–462. - PubMed
    3. Joffe S, Cook E, Cleary P, et al. Quality of informed consent in cancer clinical trials: A cross-sectional survey. Lancet. 2001;358:1772–1777. - PubMed
    4. Kass NE, Sugarman J, Faden R, Schoch-Spana M. Trust: The fragile foundation of contemporary biomedical research. Hastings Center Report. 1996;26:25–29. - PubMed

    1. See ref. 1, Joffe et al. Appelbaum PS, Roth LH, Lidz CW, et al. False hopes and best data: Consent to research and the therapeutic misconception. Hastings Center Report. 1987;17:20–24. 2001.Lesko LM, Dermatis H, Penman D, et al. Patients’, parents’, and oncologists’ perceptions of informed consent for bone marrow transplantation. Medical and Pediatric Oncology. 1989;17:181–187.Howard JM, DeMets D. How informed is informed consent? The BHAT experience. Controlled Clinical Trials. 1981;2:287–303.Snowdon C, Garcia J, Elbourne D. Making sense of randomization: Responses of parents of critically ill babies to random allocation of treatment in a clinical trial. Social Science and Medicine. 1997;45:1337–1355.Benson P, Roth LH, Winslade W. Informed consent in psychiatric research: Preliminary findings from an ongoing investigation. Social Science and Medicine. 1985;20:1331–1341.Robinson EJ, Kerr CE, Stevens AJ, et al. Lay public’s understanding of equipoise and randomization in randomized controlled trials. Health Technology Assessment. 2005;9(8):1–196.Henderson GE, Churchill LR, Davis AM, et al. Clinical trials and medical care: Defining the therapeutic misconception. Public Library of Science. 2007;4(11):e324.

    1. See ref. 1, Joffe et al. 2001.

    1. Daugherty CK, Banik DM, Janish L, et al. Quantitative analysis of ethical issues in phase I trials: A survey interview study of 144 advanced cancer patients. IRB: Ethics & Human Research. 2000;22(3):6–14. - PubMed
    1. Kass N, Sugarman J, Taylor H, et al. Purpose and benefits of early phase clinical trials: What do oncologists say? What do patients hear? Journal of Empirical Research on Human Research Ethics. 2008;3(3):57–68. - PMC - PubMed
    2. Meropol NJ, Weinfurt KP, Burnett CB, et al. Perceptions of patients and physicians regarding phase I cancer clinical trials: Implications for physician-patient communication. Journal of Clinical Oncology. 2003;21 (13):2589–2596. - PubMed

Publication types

MeSH terms

LinkOut - more resources