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Comment
. 2009 Jun 30;106(26):10402-3.
doi: 10.1073/pnas.0905226106. Epub 2009 Jun 24.

Old substrates for new enzymes of terpenoid biosynthesis

Jörg Bohlmann  1 , Jonathan Gershenzon
Affiliations
Comment

Old substrates for new enzymes of terpenoid biosynthesis

Jörg Bohlmann et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Type I and type VI glandular trichomes on the stems and the leaf veins of the cultivated tomato (Solanum lycopersicum). The tiny type VI glandular hairs contain specialized cells for the formation of terpenoid volatile compounds. Using cell-type-specific ultrahigh-throughput transcriptome sequencing combined with metabolite profiling, genetic analysis, and biochemical characterization of heterologously expressed enzymes, Schilmiller et al. (1) discovered that neryl diphosphate (NPP), rather than the classical geranyl diphosphate (GPP), is the biologically relevant intermediate in the biosynthesis of tomato monoterpenes. Micrographs were taken by Anthony Schilmiller (Michigan State University, East Lansing).
See this image and copyright information in PMC

Comment on

References

    1. Schilmiller AL, et al. Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. Proc Natl Acad Sci USA. 2009;106:10865–10870. - PMC - PubMed
    1. Gershenzon J, Dudareva N. The function of terpene natural products in the natural world. Nat Chem Biol. 2007;3:408–414. - PubMed
    1. Bohlmann J, Keeling CI. Terpenoid biomaterials. Plant J. 2008;54:656–669. - PubMed
    1. Bohlmann J, Meyer-Gauen G, Croteau R. Plant terpenoid synthases: Molecular biology and phylogenetic analysis. Proc Natl Acad Sci USA. 1998;95:4126–4133. - PMC - PubMed
    1. Tholl D. Terpene synthases and the regulation, diversity and biological roles of terpene metabolism. Curr Opin Plant Biol. 2006;9:297–304. - PubMed

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