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Case Reports
. 2007 Fall;15(3):165-8.
doi: 10.1177/229255030701500306.

Extraskeletal Ewing's sarcoma in a great toe of a young boy

Tatiana Karine Simon Cypel  1 , Benjamin Meilik, Ronald Melvin Zuker
Affiliations
Case Reports

Extraskeletal Ewing's sarcoma in a great toe of a young boy

Tatiana Karine Simon Cypel et al. Can J Plast Surg. 2007 Fall.

Abstract
in English, French

Extraskeletal Ewing's sarcoma (EES) is a rare, soft tissue, malignant neoplasm histologically similar to skeletal Ewing's sarcoma. It occurs mainly in adolescents and young adults, and affects extremities in 36% of cases and central locations (commonly paravertebral regions) in the remainder. The differential diagnosis includes other small, blue, round cell tumours. A clinical case of EES involving a great toe in a young boy is reported. EES diagnosis was confirmed by features of histological analysis and immunohistochemistry, and by the presence of the t(11;22) chromosomal translocation.

Le sarcome d’Ewing extrasquelettique (SEE) est une rare néoplasie des tissus mous semblable au sarcome d’Ewing squelettique sur le plan histologique. Il survient le plus souvent chez les adolescents et les jeunes adultes; il affecte les membres dans 36 % des cas et a une localisation centrale (souvent les régions paravertébrales) dans les autres cas. Le diagnostic différentiel inclut d’autres tumeurs à petites cellules, à cellules rondes et à cellules bleues. On présente ici un cas clinique de SEE affectant le gros orteil d’un garçonnet. Le diagnostic de SEE a été confirmé par la présence d’anomalies caractéristiques aux analyses histologique et immunohistochimique et la présence de la translocation chromosomique t(11;22).

Keywords: Ewing’s sarcoma; Extraskeletal; Great toe.

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Figures

Figure 1)
Figure 1)
Extraskeletal Ewing’s sarcoma lesion before excisional biopsy
Figure 2)
Figure 2)
Surgical plan for definitive amputation
Figure 3)
Figure 3)
Final surgical outcome
See this image and copyright information in PMC

References

    1. Marec-Bérard P, Philip T. Ewing sarcoma: The pediatrician’s point of view. Pediatr Blood Cancer. 2004;42:477–80. - PubMed
    1. Kushner BH, Hajdu SI, Gulati SC, Erlandson RA, Exelby PR, Lieberman PH. Extracranial primitive neuroectodermal tumors. The Memorial Sloan-Kettering Cancer Center experience. Cancer. 1991;67:1825–9. - PubMed
    1. Siegel RD, Ryan LM, Antman KH. Adults with Ewing’s sarcoma. An analysis of 16 patients at the Dana-Farber Cancer Institute. Am J Clin Oncol. 1988;11:614–7. - PubMed
    1. Maygarden SJ, Askin FB, Siegal GP, et al. Ewing sarcoma of bone in infants and toddlers. A clinicopathologic report from the Intergroup Ewing’s Study. Cancer. 1993;71:2109–18. - PubMed
    1. Bernstein M, Randall R, Juergens H, et al. Ewing’s sarcoma family of tumors: Ewing’s sarcoma of bone and soft tissue and peripheral primitive neuroectodermal tumors. In: Pizzo PA, Poplack DG, editors. Principles and Practice of Pediatric Oncology. 5th edn. Hagerstown: Lippincott Williams & Wilkins; 2006. pp. 1002–32.

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