Things that go BMP in the liver: bone morphogenetic protein 6 and the control of body iron homeostasis

Affiliations

Comment

Gregory J Anderson. Hepatology. 2009 Jul.

. 2009 Jul;50(1):316-9.

doi: 10.1002/hep.23106.

¹ Iron Metabolism Laboratory, Queensland Institute of Medical Research, Brisbane, Australia.

No abstract available

Comment on

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Andriopoulos B Jr, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL. Andriopoulos B Jr, et al. Nat Genet. 2009 Apr;41(4):482-7. doi: 10.1038/ng.335. Epub 2009 Mar 1. Nat Genet. 2009. PMID: 19252486 Free PMC article.
Lack of the bone morphogenetic protein BMP6 induces massive iron overload.
Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP. Meynard D, et al. Nat Genet. 2009 Apr;41(4):478-81. doi: 10.1038/ng.320. Epub 2009 Mar 1. Nat Genet. 2009. PMID: 19252488