Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2009 Sep;47(3):347-9.
doi: 10.1016/j.yjmcc.2009.06.011. Epub 2009 Jun 22.

Stressing the giant: a new approach to understanding dilated cardiomyopathy

Editorial

Stressing the giant: a new approach to understanding dilated cardiomyopathy

Marion Lewis Greaser. J Mol Cell Cardiol. 2009 Sep.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Diagram of human titin regions and locations of mutations in the half sarcomere. The single titin molecules extend from the Z-line to the M-line in the middle of the sarcomere. The I-band region background is shown in yellow and the A-band region in white. Each number listed refers to a single titin mutation in the corresponding exon annotated in GenBank AJ277892. The mutation for the knockin-mouse report in the current issue [30] is denoted with an asterisk.

Comment on

References

    1. Ahmad F, Seidman JG, Seidman CE. The genetic basis for cardiac remodeling. Annu Rev Genomics Hum Genet. 2005;6:185–216. - PubMed
    1. Bos JM, Ommen SR, Ackerman MJ. Genetics of hypertrophic cardiomyopathy: one, two, or more diseases? Curr Opin Cardiol. 2007;22:193–9. - PubMed
    1. Marian AJ. Genetic determinants of cardiac hypertrophy. Curr Opin Cardiol. 2008;23:199–205. - PMC - PubMed
    1. Oldfors A, Lamont PJ. Thick filament diseases. Adv Exp Med Biol. 2008;642:78–91. - PubMed
    1. Tsoutsman T, Bagnall RD, Semsarian C. Impact of multiple gene mutations in determining the severity of cardiomyopathy and heart failure. Clin Exp Pharmacol Physiol. 2008;35:1349–57. - PubMed