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Clinical Trial
. 1991 Sep;54(9):813-6.
doi: 10.1136/jnnp.54.9.813.

A double blind trial of botulinum toxin "A" in torticollis, with one year follow up

A P Moore  1 , L D Blumhardt
Affiliations
Clinical Trial

A double blind trial of botulinum toxin "A" in torticollis, with one year follow up

A P Moore et al. J Neurol Neurosurg Psychiatry. 1991 Sep.

Abstract

A double blind placebo controlled crossover trial was performed of botulinum toxin "A" in 20 patients with spasmodic torticollis. There was a statistically significant benefit for those treated with toxin; 12 on toxin improved objectively, compared with four on placebo (p less than 0.04). After a follow up period of one year, 16 still seemed to benefit from repeated toxin injections. The main side effect was dysphagia, which appeared to be dose related in individual patients.

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